Articles: Volume 21.04 October-December 2017

Daclizumab: another option for highly active relapsing-remitting MS

Daclizumab provides clinicians with a new treatment option for patients with relapsing-remitting multiple sclerosis. Here the authors consider its benefits compared with other multiple sclerosis drugs and its likely place in therapy

More details...

SSRI-induced severe adverse cutaneous reaction – a case report

As selective serotonin re-uptake inhibitors (SSRIs) are commonly prescribed, less common side-effects such as severe adverse cutaneous drug reactions (ACDRs) can be seen more frequently than with less frequently prescribed antidepressants. Sertraline is among the better tolerated SSRIs. Here, we describe a case of a sertraline-induced severe ACDR in a patient with depressive symptoms and cognitive impairment. A review of recent literature on the clinical and temporal presentation of SSRI-induced ACDRs is presented with management strategies

More details...

A case report of olanzapine and related cardiac conduction changes

The use of certain psychotropic medications can be associated with serious ventricular arrhythmia and sudden cardiac death. In this article, the authors use the QTc value in a patient treated with olanzapine for psychotic depression to highlight the challenges in balancing psychotropic medication against cardiac conduction changes

More details...

Recurrent transient global amnesia: is there a link to familial history?

Although most episodes of transient global amnesia (TGA) are single or unique, there is a low recurrence rate. The factors associated with recurrence are uncertain. In this article, Dr Larner describes a patient with recurrent TGA and a positive family history, which prompted consideration of the possible role of genetic factors in TGA recurrence

More details...

Association between antipsychotics and adverse outcomes in dementia

Prolonged use of antipsychotics continues to be a controversial subject area, especially in the older adult population due to age-related changes in pharmacokinetic and pharmacodynamics parameters. Best practice guidelines recommends that they should be used at their lowest dosage for no longer than 6–12 weeks. Here, the authors discuss the prevalence of antipsychotic use to treat the behavioural and psychological symptoms of dementia in the older adult population and the dilemma it poses

More details...

Mental Health 2017: Implementing the Five Year Forward View

At the Mental Health 2017: Implementing the Five Year Forward View conference held in September 2017 at the Royal Society of Medicine, delegates were informed on current government plans to focus attention on perinatal and children’s mental health, to bring mental health care from institutions into the community and to integrate physical and mental health services. Felix David here reports on some of the conference highlights

More details...

For everything there is a season: biological rhythms in psychiatry

A new study suggests that a circadian clock gene expressed in skeletal muscle may influence recovery from sleep deprivation, in mice at least. A greater understanding of such mechanisms may provide insights into one of the basic rhythms that rules our lives and disorders associated with disrupted sleep patterns

More details...

Web design and marketing agency Leamington Spa