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Latest News

Statistics on disability in primary care

NHS Digital has published ‘experimental statistics’ on people with a learning disability in primary care in England...Read more

Machine learning beats clinical prediction for resistant depression

Patients whose depression is likely to be resistant to treatment with antidepressants can be identified with a high degree of accuracy using machine learning,...Read more

Immunological strategies tackle Alzheimer’s disease

The first human trial of Axon Neuroscience’s AADvac1 vaccine against tau protein is generally reassuring. In 30 people with mild to moderate Alzheimer’s...Read more

Amitriptyline and topiramate no better than placebo for childhood migraine

Amitriptyline and topiramate are no better than placebo in the prophylaxis of migraine in children, say US investigators. Their 24-week trial sought a 50%...Read more

Gabapentin may worsen sleep

Gabapentin may worsen breathing during sleeping in non-obese men, according to a small study. This double-blind trial used polysomnography to evaluate the...Read more

Featured Articles

Frequency of change of diagnoses in first-episode psychosis
Early diagnosis and appropriate psychoeducation is crucial to the role of an early intervention in psychosis team. However, diagnostic uncertainty in first-episode psychosis in young people has to be acknowledged. Here, the authors examine the frequency with which diagnoses of psychotic disorders change between entry and exit from an EIP team and the practical implications for relevant psychoeducation.
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Diagnostic test accuracy of cognitive screeners in older people
Age is a key risk factor for cognitive impairment and dementia. Here, the authors re-analyse data from several pragmatic diagnostic test accuracy studies examining various short cognitive screening instruments (CSIs) in a secondary-care, neurology-led, cognitive disorders clinic and establish whether any CSI tests are more favourable in the older age group.
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Psychiatric manifestations of toxocara
Psychiatric patients are more likely than the general population to be at risk from toxocara. Here, the authors discuss a case that highlights that it is prudent to consider atypical pathogens in patients presenting with an unexplained high eosinophil count, or if there has been a history of homelessness, farm work or contact with animals.
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